The background of this research was based on the phenomenon that most students feel bored while learning vocabulary through paper-based. In other to create an interesting teaching and enjoyable activity in the classroom, the teacher should be able to use various media such as internet or other innovative media.. In this occassion, the researcher used Quizizz to teach vocabulary. This study is aimed to explain the effectiveness of using Quizizz to teach voabulary. This research discusses the difference between using Quizizz in teaching vocabulary at the fifth grade of SD Islam Al Azhar 29 BSB Semarang in The Academic Year of 2019/2020. The method used in this research is quantitative research and the research design used an experimental research. The sample of the research were 5 Isa as experimental class and 5 Yunus as control class. The experimental class was taught using Quizizz and the control class was taught without Quizizz. The writer used test instruments (pre-test and post- test). Based on the collecting data, The average post-test of experimental class was 8.36 and control class was 7.73. On the hypothetical test was obtained p value = 0,043295 with significant level of α = 0.05, it showed that p value > α (0.043295 > 0.05), so Ho was rejected and Ha is accepted. It means that, there is a significant difference in students’ vocabulary between who were taught using Quizizz and without Quizizz. Based on the results, it can be concluded that the use of Quizizz in teaching vocabulary is effective. Therefore, it is recommended that Quizizz can be one way in teaching English vocabulary.