This thesis discusses the phenomenon of childfree according to Sayyid Mahmud al-Alusi in Tafsir Rūḥ al-Ma’ānī. Childfree is not explicitly discussed in the Qur'an. However, implicitly the author finds three verses that discuss the childfree background, namely, QS. al-Isra’ [17]: 31, QS. al-An’am [6]: 151 and QS. an-Nisa’ [4]: 9. The popularity of the childfree trend has recently made scholars present arguments to each other, both defense and rejection. The purpose of this study is to describe how childfree is in the perspective of al-Alusi’s interpretation. This research is library research. The main source is taken from Tafsir Rūḥ al-Ma’ānī. Meanwhile, secondary sources are taken from various books, books, journals, and scientific papers that discuss issues relevant to this research. The method used is the descriptive-analytical method. While the theory used to analyze the problem is the hermeneutics of Hans Gadamer. The theory of Gadamer generally uses three stages, namely, First, awareness of the hermeneutic situation, namely the researcher must know between the pre-understanding of the text (verse) and the pre-understanding of the reader (al-Alusi). Second, the blurring of the text horizon and the reader's horizon. The horizon of the text in the context of this interpretation is called asbāb an-nuzūl both micro and macro. While the reader's horizon according to Gadamer only acts as a stepping point for someone in understanding the text which in this case is the interpretation of al-Alusi. Third, application theory and interpretation. The application theory proposed by Gadamer is that after the interpreter finds the meaning intended by a text, then the development of interpretation is carried out while still paying attention to the continuity of the new meaning with the original meaning of the text. The results of this research analysis show that al-Alusi’s textual interpretation does not prohibit the option to be childfree. However, al-Alusi’s interpretation indicates that regardless of any reason he disagreed with childfree. Because it is tantamount to murder both in essence, pilgrims (next generation) and mental killing. In addition, according to al-Alusi, concern for children is tantamount to doubting the power of Allah. The relevance of al-Alusi’s interpretation of the childfree phenomenon in QS. al-An’am [6]: 151, QS. al-Isra’ [17]: 31 and QS. an-Nisa’ [4]: 9 presents several aspects or backgrounds that influence married couples to do childfree, namely; economic aspects, environmental or cultural aspects, psychological aspects, and sociological aspects.