Speaking is one of the four English skills that play an essential role in learning English. Therefore, someone must have good speaking skills to be able to formulate a speech fluently. Most students cannot speak fluently because they lack of pronunciation and lack of self-confidence. This research used to see the influence among the variables: (1) students’ pronunciation (X1) and speaking ability (Y), (2) students’ self-confidence (X2) and speaking ability (Y), and (3) students’pronunciation, self-confidence, and speaking ability. The method used in this research was a quantitative method and the design was a correlational study. This research population consisted of 109 fourth-semester students of English Education UIN Walisongo, Semarang in the 2019/2020 academic year. The sample in this research was 33 students who come from PBI A, PBI B, and PBI C by using a simple random sampling technique. These research instruments were students’ pronunciation test, questionnaire of self-confidence, and speaking test. This research used multiple regression and correlation analysis to find out the influence between the variables. The research finding indicated that (1) there was a positive and significant influence of students' pronunciation toward their speaking ability with a correlation coefficient of 0.443 with sig. value 0.005 < 0.05. (2) there was a positive and significant influence of students' self-confidence toward their speaking ability with a correlation coefficient of 0.220 with sig. value 0.010 < 0.05. (3) there was a positive and significant influence of students' pronunciation and self-confidence toward their speaking ability with the multiple correlation coefficient of 0.451 with sig. value 0.033 < 0.05. Since the R-Square was 0.204, it also indicated that students’ pronunciation and self-confidence simultaneously had significant influence only in the level of 20.4% toward their speaking ability, and 79.6% was unexplained factors that affected students' speaking ability. Based on the research results, it is important for English teachers and students to realize that students' pronunciation and self-confidence also have a significant influence on students' speaking ability. Therefore, students need to enhance their pronunciation and self-confidence in order to have good speaking skills. Because the better the students' pronunciation and the more confident a student is, the better their speaking ability will be.