The trend of 21st-century learning, which integrates learning, literacy, and life skills, has demanded that educators be more adaptable and creative in teaching. Digital storytelling (DST) becomes the ideal medium to promote 21st-century learning skills that collaborate with typical literacies. This research aims to explain the DST learning media to facilitate students’ speaking ability and describe their views on its implementation. Prezi becomes the chosen tool as the web-based application in creating DST. By using the case study method, this research describes the whole phenomenon in the DST teaching-learning process. The participants were six students in grade eleven of M.A. Miftahul Huda Tayu. The data was obtained from the teacher’s reflection during the learning process and student questionnaires. This study concludes that DST learning using Prezi can be suitable for facilitating students speaking ability. DST polishes both students’ language skills and technological skills. Prezi was considered the right tool for creating a DST project because of its unique presentation feature. However, the teacher needs to consider some barriers in conducting DST learning.